Catalog Number - 85518-PG2

The 85518‑PG2 Cogent RP C18 ABX™ Guard Column Cartridges are engineered to extend analytical column life while maintaining consistent chromatographic performance, protecting systems from particulates, matrix interference, and strongly retained analytes.

Packed with 5 µm RP C18 ABX™ stationary phase, these cartridges feature bulky end‑capping on high‑purity silica, ensuring stable operation across extreme pH conditions (2–12).

Designed for Analytical Columns (3.0–4.6 mm ID)

• Compatible with:

  • 3.0 mm ID solvent‑saving columns

  • 4.0 mm ID analytical columns

  • 4.6 mm ID standard HPLC columns

✅ Maintains method selectivity and chromatographic consistency

Purpose of Guard Columns

• Protect analytical columns from:

  • Particulate contamination

  • Strongly retained acidic and basic compounds

  • Sample matrix buildup and fouling

• Extend column lifetime

• Maintain retention reproducibility and peak shape

• Reduce downtime and replacement costs

5 µm Guard Media – Balanced Analytical Protection

• Matches standard analytical column particle sizes

• Provides balanced efficiency and durability

• Ideal for routine analytical and QC workflows

✅ Preferred for method reproducibility and consistent long‑term performance

Why Choose RP C18 ABX™ Guard Cartridges (5 µm)

Matched Extreme pH Chemistry

• Same ABX™ stationary phase as analytical column

• Maintains retention behavior and selectivity

• Supports full pH 2–12 operation

Enhanced Column Protection

• Captures contaminants before reaching the column

• Reduces irreversible adsorption and degradation

Workflow Efficiency

• Minimizes column replacement frequency

• Improves system uptime and reliability

Cogent RP C18 ABX™ Advantages

Extreme pH Stability

• Reliable across pH 2–12

• Ideal for acidic and basic separations

Bulky End‑Capping

• Reduces secondary interactions

• Improves peak symmetry and reproducibility

Durable Construction

• Stainless steel cartridge body

• Stainless steel frits

• PEEK frit caps

✅ Designed for long‑term analytical reliability

Important Usage Notes

• ⚠️ Must be used with a compatible guard column holder system

• Designed for analytical HPLC systems (3.0–4.6 mm ID columns)

• Suitable for extreme pH workflows (pH 2–12)

• Replace regularly to maintain optimal column protection and system performance

Helpful Resource & Link

• 👉 View guard column holders and compatibility options for these cartridges